DeBrosse, de Brosse, de La Brosse, or de la Broce is a French surname. Notable people with the surname include:

• Pierre de la Broce (died 1278), French councilor to Phillip III
• Jean de Brosse (1375–1433), Marshal of France
• Jean II de Brosse (1432–1482), chamberlain to the King of France
• Claudine de Brosse (1450–1513), French noble
• Jacques de la Brosse (c. 1485–1562), French soldier and diplomat, cupbearer to Francis I
• Jean III de Brosse (died 1502), French noble
• René de Brosse (died 1525), French noble and soldier
• Jean IV de Brosse (1505–1564), French noble
• Salomon de Brosse (1571–1626), French architect
• Guy de La Brosse (1586–1641), French botanist, doctor, and pharmacist
• Joseph de la Brosse (1636–1697), known as Ange de Saint Joseph
• Charles de Brosses (1709–1777), French noble and writer
• Simon de La Brosse (1965–1998), French actor
• Joasil Déméus Débrosse (1968–2013), Haitian journalist
• Laurent Debrosse (born 1969), French footballer